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Inhibition of Plasmid Conjugation in Escherichia coli by Targeting rbsB Gene Using CRISPRi System

Bacterial conjugation constitutes a major horizontal gene transfer mechanism for the dissemination of antibiotic-resistant genes (ARGs) among human pathogens. The spread of ARGs can be halted or diminished by interfering with the conjugation process. In this study, we explored the possibility of usi...

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Detalles Bibliográficos
Autores principales: Xiao, Yawen, Zhang, Yan, Xie, Fengjun, Olsen, Rikke Heidemann, Shi, Lei, Li, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342112/
https://www.ncbi.nlm.nih.gov/pubmed/37445761
http://dx.doi.org/10.3390/ijms241310585