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Microbial Metabolites of 3-n-butylphthalide as Monoamine Oxidase A Inhibitors

Novel compounds with antidepressant activity via monoamine oxidase inhibition are being sought. Among these, derivatives of 3-n-butylphthalide, a neuroprotective lactone from Apiaceae plants, may be prominent candidates. This study aimed to obtain the oxidation products of 3-n-butylphthalide and scr...

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Detalles Bibliográficos
Autores principales: Gach, Joanna, Grzelczyk, Joanna, Strzała, Tomasz, Boratyński, Filip, Olejniczak, Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342118/
https://www.ncbi.nlm.nih.gov/pubmed/37445788
http://dx.doi.org/10.3390/ijms241310605