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Harnessing Autophagy to Overcome Antigen-Specific T-Cell Dysfunction: Implication for People Living with HIV-1

Like other chronic viral infections, HIV-1 persistence inhibits the development of antigen-specific memory T-cells, resulting in the exhaustion of the immune response and chronic inflammation. Autophagy is a major lysosome-dependent mechanism of intracellular large-target degradation such as lipid a...

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Detalles Bibliográficos
Autores principales: Ghahari, Nazanin, Telittchenko, Roman, Loucif, Hamza, Isnard, Stephane, Routy, Jean-Pierre, Olagnier, David, van Grevenynghe, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342174/
https://www.ncbi.nlm.nih.gov/pubmed/37446195
http://dx.doi.org/10.3390/ijms241311018