Cargando…

Harnessing Autophagy to Overcome Antigen-Specific T-Cell Dysfunction: Implication for People Living with HIV-1

Like other chronic viral infections, HIV-1 persistence inhibits the development of antigen-specific memory T-cells, resulting in the exhaustion of the immune response and chronic inflammation. Autophagy is a major lysosome-dependent mechanism of intracellular large-target degradation such as lipid a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ghahari, Nazanin, Telittchenko, Roman, Loucif, Hamza, Isnard, Stephane, Routy, Jean-Pierre, Olagnier, David, van Grevenynghe, Julien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342174/ https://www.ncbi.nlm.nih.gov/pubmed/37446195 http://dx.doi.org/10.3390/ijms241311018

Ejemplares similares

Cannabinoid-Induced Immunomodulation during Viral Infections: A Focus on Mitochondria
por: Beji, Cherifa, et al.
Publicado: (2020)

USP18 is a significant driver of memory CD4 T-cell reduced viability caused by type I IFN signaling during primary HIV-1 infection
por: Dagenais-Lussier, Xavier, et al.
Publicado: (2019)

Never say “never the twain shall meet”: Combining antiretroviral therapy and RNA vaccine to obtain an adequate humoral immune response in people living with HIV
por: Routy, Jean-Pierre, et al.
Publicado: (2022)

Cytomegalovirus as an Uninvited Guest in the Response to Vaccines in People Living with HIV
por: Royston, Léna, et al.
Publicado: (2021)

Sustained IFN-I Expression during Established Persistent Viral Infection: A “Bad Seed” for Protective Immunity
por: Dagenais-Lussier, Xavier, et al.
Publicado: (2017)

HTLV-1 Tax-Mediated Inhibition of FOXO3a Activity Is Critical for the Persistence of Terminally Differentiated CD4(+) T Cells
por: Olagnier, David, et al.
Publicado: (2014)

Use of various immunotherapies for refractory ulcerative colitis in a person living with HIV: a case report
por: Costiniuk, Cecilia T, et al.
Publicado: (2021)

Control of porphyria cutanea tarda with anti-IL-17 secukinumab in a person with psoriasis living with HIV
por: Bedier, Helbies, et al.
Publicado: (2023)

Relevance of biomarkers indicating gut damage and microbial translocation in people living with HIV
por: Ouyang, Jing, et al.
Publicado: (2023)

The TLR7/IRF-5 axis sensitizes memory CD4(+) T cells to Fas-mediated apoptosis during HIV-1 infection
por: Carmona-Pérez, Liseth, et al.
Publicado: (2023)

Alcohol Use and Abuse Conspires With HIV Infection to Aggravate Intestinal Dysbiosis and Increase Microbial Translocation in People Living With HIV: A Review
por: Yan, Jiangyu, et al.
Publicado: (2021)

Beyond the Absence of CD4 T-Cell Count: A Novel Genetic CD4 T-Cell Deficiency Disorder With a Contingency Plan
por: Routy, Jean-Pierre, et al.
Publicado: (2021)

Harnessing autophagy to overcome mitogen‐activated protein kinase kinase inhibitor‐induced resistance in metastatic melanoma
por: Verykiou, S., et al.
Publicado: (2018)

The RyfA small RNA regulates oxidative and osmotic stress responses and virulence in uropathogenic Escherichia coli
por: Bessaiah, Hicham, et al.
Publicado: (2021)

Harnessing Aptamers to Overcome Challenges in Gluten Detection
por: Miranda-Castro, Rebeca, et al.
Publicado: (2016)

Harnessing nanomedicine to overcome the immunosuppressive tumor microenvironment
por: Sun, Bo, et al.
Publicado: (2020)

The Influence of Oral Terbinafine on Gut Fungal Microbiome Composition and Microbial Translocation in People Living with HIV Treated for Onychomycosis
por: Ouyang, Jing, et al.
Publicado: (2023)

Study on the Occurrence of Genetic Exchange Among Parasites of the Leishmania mexicana Complex
por: Telittchenko, Roman, et al.
Publicado: (2020)

Following the elite: Targeting immunometabolism to limit HIV pathogenesis
por: Routy, Jean-Pierre, et al.
Publicado: (2019)

Differences in HIV burden in the inflamed and non-inflamed colon from a person living with HIV and ulcerative colitis
por: Peng, Xiaorong, et al.
Publicado: (2021)

GDF15/GFRAL Pathway as a Metabolic Signature for Cachexia in Patients with Cancer
por: Ahmed, Darakhshan Sohail, et al.
Publicado: (2021)

Harnessing Noxa demethylation to overcome Bortezomib resistance in mantle cell lymphoma
por: Leshchenko, Violetta V., et al.
Publicado: (2015)

GDF-15 as a Weight Watcher for Diabetic and Non-Diabetic People Treated With Metformin
por: Ouyang, Jing, et al.
Publicado: (2020)

Growth differentiation factor-15 as a biomarker of atherosclerotic coronary plaque: Value in people living with and without HIV
por: Royston, Léna, et al.
Publicado: (2022)

Harnessing Ferroptosis to Overcome Drug Resistance in Colorectal Cancer: Promising Therapeutic Approaches
por: Cheng, Xiaofei, et al.
Publicado: (2023)

Harnessing Dendritic Cells for Tumor Antigen Presentation
por: Nierkens, Stefan, et al.
Publicado: (2011)

Editorial: Harnessing autophagy to improve plant quality and resilience
por: Signorelli, Santiago, et al.
Publicado: (2023)

Metformin effect on gut microbiota: insights for HIV-related inflammation
por: Ouyang, Jing, et al.
Publicado: (2020)

Overcoming the UCB HSCs –Derived NK cells Dysfunction through Harnessing RAS/MAPK, IGF-1R and TGF-β Signaling Pathways
por: Shokouhifar, Alireza, et al.
Publicado: (2021)

Camu Camu effects on microbial translocation and systemic immune activation in ART-treated people living with HIV: protocol of the single-arm non-randomised Camu Camu prebiotic pilot study (CIHR/CTN PT032)
por: Isnard, Stéphane, et al.
Publicado: (2022)

Harnessing C/N balance of Chromochloris zofingiensis to overcome the potential conflict in microalgal production
por: Sun, Han, et al.
Publicado: (2020)

Cytomegalovirus Seropositivity Is Associated With Increased Microbial Translocation in People Living With Human Immunodeficiency Virus and Uninfected Controls
por: Ramendra, Rayoun, et al.
Publicado: (2019)

Harnessing the liver to induce antigen-specific immune tolerance
por: Gottwick, Cornelia, et al.
Publicado: (2022)

Harnessing the Interaction Continuum for Subtle Assisted Living
por: García-Herranz, Manuel, et al.
Publicado: (2012)

Targeting Autophagy to Overcome Human Diseases
por: Condello, Maria, et al.
Publicado: (2019)

Gut Leakage of Fungal‐Related Products: Turning Up the Heat for HIV Infection
por: Isnard, Stéphane, et al.
Publicado: (2021)

Harnessing the p53-PUMA Axis to Overcome DNA Damage Resistance in Renal Cell Carcinoma()
por: Zhou, Xiaoguang, et al.
Publicado: (2014)

Navigating the journey of multiple sclerosis management in Africa, overcoming hurdles and harnessing opportunities: a review
por: Aderinto, Nicholas, et al.
Publicado: (2023)

Coping With Stress: The Mitokine GDF-15 as a Biomarker of COVID-19 Severity
por: Ahmed, Darakhshan Sohail, et al.
Publicado: (2022)

Harnessing molecular motors for nanoscale pulldown in live cells
por: Bird, Jonathan E., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_sgm2i9cbrq0k1utk3j0h24ludl