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Comparison of phasor analysis and biexponential decay curve fitting of autofluorescence lifetime imaging data for machine learning prediction of cellular phenotypes
Introduction: Autofluorescence imaging of the coenzymes reduced nicotinamide (phosphate) dinucleotide (NAD(P)H) and oxidized flavin adenine dinucleotide (FAD) provides a label-free method to detect cellular metabolism and phenotypes. Time-domain fluorescence lifetime data can be analyzed by exponent...
Autores principales: | Hu, Linghao, Ter Hofstede, Blanche, Sharma, Dhavan, Zhao, Feng, Walsh, Alex J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342207/ https://www.ncbi.nlm.nih.gov/pubmed/37455808 http://dx.doi.org/10.3389/fbinf.2023.1210157 |
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