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Treatment-Resistant Depression (TRD): Is the Opioid System Involved?

About 30% of major depression disorder patients fail to achieve remission, hence being diagnosed with treatment-resistant major depression (TRD). Opium had been largely used effectively to treat depression for centuries, but when other medications were introduced, its use was discounted due to addic...

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Detalles Bibliográficos
Autores principales: Schreiber, Shaul, Keidan, Lee, Pick, Chaim G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342252/
https://www.ncbi.nlm.nih.gov/pubmed/37446323
http://dx.doi.org/10.3390/ijms241311142