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Dopamine D3 Receptor Modulates Akt/mTOR and ERK(1/2) Pathways Differently during the Reinstatement of Cocaine-Seeking Behavior Induced by Psychological versus Physiological Stress

Stress triggers relapses in cocaine use that engage the activity of memory-related nuclei, such as the basolateral amygdala (BLA) and dentate gyrus (DG). Preclinical research suggests that D3 receptor (D3R) antagonists may be a promising means to attenuate cocaine reward and relapse. As D3R regulate...

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Detalles Bibliográficos
Autores principales: Franco-García, Aurelio, Guerrero-Bautista, Rocío, Hidalgo, Juana María, Gómez-Murcia, Victoria, Milanés, María Victoria, Núñez, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342329/
https://www.ncbi.nlm.nih.gov/pubmed/37446391
http://dx.doi.org/10.3390/ijms241311214