Increased Interleukin-17-Producing γδT Cells in the Brain Exacerbate the Pathogenesis of Sepsis-Associated Encephalopathy and Sepsis-Induced Anxiety in Mice

Overactivated microglia play a key role in sepsis-associated encephalopathy (SAE), although the involvement of T cells is unclear. γδT cells in the brain and meninges regulate normal fear responses via interleukin (IL)-17 in healthy mice. In our sepsis model, the mice showed exacerbated anxious beha...

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Detalles Bibliográficos
Autores principales: Moriyama, Naoki, Saito, Masafumi, Ono, Yuko, Yamashita, Kimihiro, Aoi, Takashi, Kotani, Joji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342653/
https://www.ncbi.nlm.nih.gov/pubmed/37445343
http://dx.doi.org/10.3390/jcm12134309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342653/
https://www.ncbi.nlm.nih.gov/pubmed/37445343
http://dx.doi.org/10.3390/jcm12134309

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