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Lamivudine (3TC), a Nucleoside Reverse Transcriptase Inhibitor, Prevents the Neuropathological Alterations Present in Mutant Tau Transgenic Mice

The dysregulation of transposable elements contributes to neurodegenerative disorders. Previous studies have reported an increase in retrotransposon transcription in Drosophila models as well as in human tauopathies. In this context, we tested the possible protective effects of a reverse transcripta...

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Detalles Bibliográficos
Autores principales: Vallés-Saiz, Laura, Ávila, Jesús, Hernández, Félix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342792/
https://www.ncbi.nlm.nih.gov/pubmed/37446327
http://dx.doi.org/10.3390/ijms241311144