Neurodegenerative Disease Associated Pathways in the Brains of Triple Transgenic Alzheimer’s Model Mice Are Reversed Following Two Weeks of Peripheral Administration of Fasudil

The pan Rho-associated coiled-coil-containing protein kinase (ROCK) inhibitor fasudil acts as a vasodilator and has been used as a medication for post-cerebral stroke for the past 29 years in Japan and China. More recently, based on the involvement of ROCK inhibition in synaptic function, neuronal s...

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Detalles Bibliográficos
Autores principales: Killick, Richard, Elliott, Christina, Ribe, Elena, Broadstock, Martin, Ballard, Clive, Aarsland, Dag, Williams, Gareth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342807/
https://www.ncbi.nlm.nih.gov/pubmed/37446396
http://dx.doi.org/10.3390/ijms241311219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342807/
https://www.ncbi.nlm.nih.gov/pubmed/37446396
http://dx.doi.org/10.3390/ijms241311219

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