Interplay between Diffusion and Bond Cleavage Reaction for Determining Release in Polymer–Drug Conjugates

In conjugated polymeric drug delivery systems, both the covalent bond degradation rate and the diffusion of the freely moving drug particles affect the release profile of the formulation. Using Monte Carlo simulations in spherical matrices, the release kinetics resulting from the competition between...

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Detalles Bibliográficos
Autor principal: Kalosakas, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342812/
https://www.ncbi.nlm.nih.gov/pubmed/37444909
http://dx.doi.org/10.3390/ma16134595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342812/
https://www.ncbi.nlm.nih.gov/pubmed/37444909
http://dx.doi.org/10.3390/ma16134595

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