Telling Your Right Hand from Your Left: The Effects of DNA Supercoil Handedness on the Actions of Type II Topoisomerases

Type II topoisomerases are essential enzymes that modulate the topological state of DNA supercoiling in all living organisms. These enzymes alter DNA topology by performing double-stranded passage reactions on over- or underwound DNA substrates. This strand passage reaction generates a transient cov...

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Detalles Bibliográficos
Autores principales: Jian, Jeffrey Y., Osheroff, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342825/
https://www.ncbi.nlm.nih.gov/pubmed/37446377
http://dx.doi.org/10.3390/ijms241311199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342825/
https://www.ncbi.nlm.nih.gov/pubmed/37446377
http://dx.doi.org/10.3390/ijms241311199

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