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Hybrid Molecules of Benzylguanidine and the Alkylating Group of Melphalan: Synthesis and Effects on Neuroblastoma Cells

The therapy of neuroblastoma relies, amongst other things, on administering chemotherapeutics and radioactive compounds, e.g., the (meta-iodobenzyl)guanidine [(131)I]mIBG. For special applications (conditioning before stem cell transplantation), busulfan and melphalan (M) proved to be effective. How...

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Detalles Bibliográficos
Autores principales: Bruchelt, Gernot, Klose, Chihab, Lischka, Matthias, Brandes, Marietta, Handgretinger, Rupert, Brueckner, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342853/
https://www.ncbi.nlm.nih.gov/pubmed/37445504
http://dx.doi.org/10.3390/jcm12134469