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Placenta-on-a-Chip as an In Vitro Approach to Evaluate the Physiological and Structural Characteristics of the Human Placental Barrier upon Drug Exposure: A Systematic Review

Quantification of fetal drug exposure remains challenging since sampling from the placenta or fetus during pregnancy is too invasive. Currently existing in vivo (e.g., cord blood sampling) and ex vivo (e.g., placenta perfusion) models have inherent limitations. A placenta-on-a-chip model is a promis...

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Detalles Bibliográficos
Autores principales: Elzinga, Femke A., Khalili, Behrad, Touw, Daan J., Prins, Jelmer R., Olinga, Peter, Leuvenink, Henri G. D., van Goor, Harry, Gordijn, Sanne J., Nagelkerke, Anika, Mian, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342880/
https://www.ncbi.nlm.nih.gov/pubmed/37445348
http://dx.doi.org/10.3390/jcm12134315