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Placenta-on-a-Chip as an In Vitro Approach to Evaluate the Physiological and Structural Characteristics of the Human Placental Barrier upon Drug Exposure: A Systematic Review
Quantification of fetal drug exposure remains challenging since sampling from the placenta or fetus during pregnancy is too invasive. Currently existing in vivo (e.g., cord blood sampling) and ex vivo (e.g., placenta perfusion) models have inherent limitations. A placenta-on-a-chip model is a promis...
Autores principales: | Elzinga, Femke A., Khalili, Behrad, Touw, Daan J., Prins, Jelmer R., Olinga, Peter, Leuvenink, Henri G. D., van Goor, Harry, Gordijn, Sanne J., Nagelkerke, Anika, Mian, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342880/ https://www.ncbi.nlm.nih.gov/pubmed/37445348 http://dx.doi.org/10.3390/jcm12134315 |
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