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Intestinal Microbiota Reduction Followed by Fasting Discloses Microbial Triggering of Inflammation in Rheumatoid Arthritis

Rheumatoid arthritis (RA) synovitis is dominated by monocytes/macrophages with inflammatory patterns resembling microbial stimulation. In search of triggers, we reduced the intestinal microbiome in 20 RA patients (open label study DRKS00014097) by bowel cleansing and 7-day fasting (≤250 kcal/day) an...

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Detalles Bibliográficos
Autores principales: Häupl, Thomas, Sörensen, Till, Smiljanovic, Biljana, Darcy, Marine, Scheder-Bieschin, Justus, Steckhan, Nico, Hartmann, Anika M., Koppold, Daniela A., Stuhlmüller, Bruno, Skriner, Karl, Walewska, Barbara M., Hoppe, Berthold, Bonin, Marc, Burmester, Gerd R., Schendel, Pascal, Feist, Eugen, Liere, Karsten, Meixner, Martin, Kessler, Christian, Grützkau, Andreas, Michalsen, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10342944/
https://www.ncbi.nlm.nih.gov/pubmed/37445394
http://dx.doi.org/10.3390/jcm12134359