Glycolytic interference blocks influenza A virus propagation by impairing viral polymerase-driven synthesis of genomic vRNA

Influenza A virus (IAV), like any other virus, provokes considerable modifications of its host cell’s metabolism. This includes a substantial increase in the uptake as well as the metabolization of glucose. Although it is known for quite some time that suppression of glucose metabolism restricts vir...

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Detalles Bibliográficos
Autores principales: Kleinehr, Jens, Schöfbänker, Michael, Daniel, Katharina, Günl, Franziska, Mohamed, Fakry Fahmy, Janowski, Josua, Brunotte, Linda, Boergeling, Yvonne, Liebmann, Marie, Behrens, Matthias, Gerdemann, Andrea, Klotz, Luisa, Esselen, Melanie, Humpf, Hans-Ulrich, Ludwig, Stephan, Hrincius, Eike R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343032/
https://www.ncbi.nlm.nih.gov/pubmed/37440521
http://dx.doi.org/10.1371/journal.ppat.1010986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343032/
https://www.ncbi.nlm.nih.gov/pubmed/37440521
http://dx.doi.org/10.1371/journal.ppat.1010986

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