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Glycolytic interference blocks influenza A virus propagation by impairing viral polymerase-driven synthesis of genomic vRNA
Influenza A virus (IAV), like any other virus, provokes considerable modifications of its host cell’s metabolism. This includes a substantial increase in the uptake as well as the metabolization of glucose. Although it is known for quite some time that suppression of glucose metabolism restricts vir...
Autores principales: | Kleinehr, Jens, Schöfbänker, Michael, Daniel, Katharina, Günl, Franziska, Mohamed, Fakry Fahmy, Janowski, Josua, Brunotte, Linda, Boergeling, Yvonne, Liebmann, Marie, Behrens, Matthias, Gerdemann, Andrea, Klotz, Luisa, Esselen, Melanie, Humpf, Hans-Ulrich, Ludwig, Stephan, Hrincius, Eike R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343032/ https://www.ncbi.nlm.nih.gov/pubmed/37440521 http://dx.doi.org/10.1371/journal.ppat.1010986 |
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