Highly mismatch-tolerant homology testing by RecA could explain how homology length affects recombination

In E. coli, double strand breaks (DSBs) are resected and loaded with RecA protein. The genome is then rapidly searched for a sequence that is homologous to the DNA flanking the DSB. Mismatches in homologous partners are rare, suggesting that RecA should rapidly reject mismatched recombination produc...

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Detalles Bibliográficos
Autores principales: Prentiss, Mara, Wang, Dianzhuo, Fu, Jonathan, Prévost, Chantal, Godoy-Carter, Veronica, Kleckner, Nancy, Danilowicz, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343044/
https://www.ncbi.nlm.nih.gov/pubmed/37440583
http://dx.doi.org/10.1371/journal.pone.0288611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343044/
https://www.ncbi.nlm.nih.gov/pubmed/37440583
http://dx.doi.org/10.1371/journal.pone.0288611

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