Cargando…

Relaxing parametric assumptions for non-linear Mendelian randomization using a doubly-ranked stratification method

Non-linear Mendelian randomization is an extension to standard Mendelian randomization to explore the shape of the causal relationship between an exposure and outcome using an instrumental variable. A stratification approach to non-linear Mendelian randomization divides the population into strata an...

Descripción completa

Detalles Bibliográficos
Autores principales: Tian, Haodong, Mason, Amy M., Liu, Cunhao, Burgess, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343089/
https://www.ncbi.nlm.nih.gov/pubmed/37390109
http://dx.doi.org/10.1371/journal.pgen.1010823