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Relaxing parametric assumptions for non-linear Mendelian randomization using a doubly-ranked stratification method
Non-linear Mendelian randomization is an extension to standard Mendelian randomization to explore the shape of the causal relationship between an exposure and outcome using an instrumental variable. A stratification approach to non-linear Mendelian randomization divides the population into strata an...
Autores principales: | Tian, Haodong, Mason, Amy M., Liu, Cunhao, Burgess, Stephen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343089/ https://www.ncbi.nlm.nih.gov/pubmed/37390109 http://dx.doi.org/10.1371/journal.pgen.1010823 |
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