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Investigating the Vital Role of the Identified Abietic Acid from Helianthus annuus L. Calathide Extract against Hyperuricemia via Human Embryonic Kidney 293T Cell Model

To explore the anti-hyperuricemia components in sunflower (Helianthus annuus L.) calathide extract (SCE), we identified abietic acid (AA) via liquid chromatography–mass spectrometry and found an excellent inhibitor of xanthine oxidase (IC(50) = 10.60 µM, Ki = 193.65 nM) without cytotoxicity. Based o...

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Detalles Bibliográficos
Autores principales: Dai, Huining, Xu, Xiao, Li, Wannan, Fu, Xueqi, Han, Weiwei, Li, Guodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343225/
https://www.ncbi.nlm.nih.gov/pubmed/37446803
http://dx.doi.org/10.3390/molecules28135141