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Combination of an Oxindole Derivative with (−)-β-Elemene Alters Cell Death Pathways in FLT3/ITD(+) Acute Myeloid Leukemia Cells

Acute myeloid leukemia (AML) is one of the cancers that grow most aggressively. The challenges in AML management are huge, despite many treatment options. Mutations in FLT3 tyrosine kinase receptors make the currently available therapies less responsive. Therefore, there is a need to find new lead m...

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Detalles Bibliográficos
Autores principales: Alanazi, Jowaher, Bender, Onur, Dogan, Rumeysa, Malik, Jonaid Ahmad, Atalay, Arzu, Ali, Taha F. S., Beshr, Eman A. M., Shawky, Ahmed M., Aly, Omar M., Alqahtani, Yasir Nasser H., Anwar, Sirajudheen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343312/
https://www.ncbi.nlm.nih.gov/pubmed/37446914
http://dx.doi.org/10.3390/molecules28135253