Computational Tool to Design Small Synthetic Inhibitors Selective for XIAP-BIR3 Domain

X-linked inhibitor of apoptosis protein (XIAP) exercises its biological function by locking up and inhibiting essential caspase-3, -7 and -9 toward apoptosis execution. It is overexpressed in multiple human cancers, and it plays an important role in cancer cells’ death skipping. Inhibition of XIAP-B...

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Detalles Bibliográficos
Autores principales: Farag, Marc, Kieffer, Charline, Guedeney, Nicolas, Voisin-Chiret, Anne Sophie, Sopkova-de Oliveira Santos, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343376/
https://www.ncbi.nlm.nih.gov/pubmed/37446817
http://dx.doi.org/10.3390/molecules28135155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343376/
https://www.ncbi.nlm.nih.gov/pubmed/37446817
http://dx.doi.org/10.3390/molecules28135155

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