Computational Insights into Novel Inhibitor N-(3-(tert-Butylcarbamoyl)-4-methoxyphenyl)-indole and Ingliforib Specific against GP Isoenzyme Dimers Interaction Mechanism

The high conservation of the three subtypes of glycogen phosphorylase (GP) presents significant challenges for specific inhibitor studies targeting GP. Our prior screening revealed that compound 1 exhibited unequal inhibitory activity against the three GP subtypes, with a noticeable effect against b...

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Detalles Bibliográficos
Autores principales: Wang, Youde, Li, Shuai, Yan, Zhiwei, Zhang, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343391/
https://www.ncbi.nlm.nih.gov/pubmed/37446571
http://dx.doi.org/10.3390/molecules28134909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343391/
https://www.ncbi.nlm.nih.gov/pubmed/37446571
http://dx.doi.org/10.3390/molecules28134909

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