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Length-Dependent Transition from Extended to Folded Shapes in Short Oligomers of an Azetidine-Based α-Amino Acid: The Critical Role of NH···N H-Bonds

Hydrogen bonds (H-bonds) are ubiquitous in peptides and proteins and are central to the stabilization of their structures. Inter-residue H-bonds between non-adjacent backbone amide NH and C=O motifs lead to the well-known secondary structures of helices, turns and sheets, but it is recognized that o...

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Detalles Bibliográficos
Autores principales: Liu, Dayi, Bardaud, Jean-Xavier, Imani, Zeynab, Robin, Sylvie, Gloaguen, Eric, Brenner, Valérie, Aitken, David J., Mons, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343408/
https://www.ncbi.nlm.nih.gov/pubmed/37446709
http://dx.doi.org/10.3390/molecules28135048