In Silico Identification of Natural Product-Based Inhibitors Targeting IL-1β/IL-1R Protein–Protein Interface

IL-1β mediates inflammation and regulates immune responses, cell proliferation, and differentiation. Dysregulation of IL-1β is linked to inflammatory and autoimmune diseases. Elevated IL-1β levels are found in patients with severe COVID-19, indicating its excessive production may worsen the disease....

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Detalles Bibliográficos
Autores principales: Liu, Ting-ting, Chen, Yan-kun, Adil, Muhammad, Almehmadi, Mazen, Alshabrmi, Fahad M., Allahyani, Mamdouh, Alsaiari, Ahad Amer, Liu, Pei, Khan, Muhammad Raheel, Peng, Qinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343601/
https://www.ncbi.nlm.nih.gov/pubmed/37446547
http://dx.doi.org/10.3390/molecules28134885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343601/
https://www.ncbi.nlm.nih.gov/pubmed/37446547
http://dx.doi.org/10.3390/molecules28134885

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