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In Silico Identification of Natural Product-Based Inhibitors Targeting IL-1β/IL-1R Protein–Protein Interface
IL-1β mediates inflammation and regulates immune responses, cell proliferation, and differentiation. Dysregulation of IL-1β is linked to inflammatory and autoimmune diseases. Elevated IL-1β levels are found in patients with severe COVID-19, indicating its excessive production may worsen the disease....
Autores principales: | Liu, Ting-ting, Chen, Yan-kun, Adil, Muhammad, Almehmadi, Mazen, Alshabrmi, Fahad M., Allahyani, Mamdouh, Alsaiari, Ahad Amer, Liu, Pei, Khan, Muhammad Raheel, Peng, Qinghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343601/ https://www.ncbi.nlm.nih.gov/pubmed/37446547 http://dx.doi.org/10.3390/molecules28134885 |
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