Design, Synthesis, and Acute Toxicity Assays for Novel Thymoquinone Derivative TQFL12 in Mice and the Mechanism of Resistance to Toxicity

TQFL12 is a novel derivative designed and synthesized on the basis of Thymoquinone (TQ) which is extracted from Nigella sativa seeds. We have demonstrated that TQFL12 was more effective in the treatment of TNBC than TQ. In order to directly reflect the acute toxicity of TQFL12 in vivo, in this study...

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Detalles Bibliográficos
Autores principales: Li, Ting, Tan, Qi, Wei, Chunli, Zou, Hui, Liu, Xiaoyan, Mei, Zhiqiang, Zhang, Pengfei, Cheng, Jingliang, Fu, Junjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343667/
https://www.ncbi.nlm.nih.gov/pubmed/37446810
http://dx.doi.org/10.3390/molecules28135149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343667/
https://www.ncbi.nlm.nih.gov/pubmed/37446810
http://dx.doi.org/10.3390/molecules28135149

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