Electrochemical Synthesis of New Isoxazoles and Triazoles Tethered with Thiouracil Base as Inhibitors of Histone Deacetylases in Human Breast Cancer Cells

Histone deacetylases (HDACs) are an attractive drug target for the treatment of human breast cancer (BC), and therefore, HDAC inhibitors (HDACis) are being used in preclinical and clinical studies. The need to understand the scope of the mode of action of HDACis, as well as the report of the co-crys...

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Detalles Bibliográficos
Autores principales: Vishwanath, Divakar, Xi, Zhang, Ravish, Akshay, Mohan, Arunkumar, Basappa, Shreeja, Krishnamurthy, Niranjan Pattehalli, Gaonkar, Santosh L., Pandey, Vijay, Lobie, Peter E., Basappa, Basappa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343668/
https://www.ncbi.nlm.nih.gov/pubmed/37446915
http://dx.doi.org/10.3390/molecules28135254

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343668/
https://www.ncbi.nlm.nih.gov/pubmed/37446915
http://dx.doi.org/10.3390/molecules28135254

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