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Design, Synthesis, Molecular Docking Study and Biological Evaluation of Novel γ-Carboline Derivatives of Latrepirdine (Dimebon) as Potent Anticancer Agents

A series of novel γ-Carboline derivatives were designed and synthesized using the Suzuki coupling reaction to identify the leads for the activity against cancer. Interestingly, these compounds were tested for their anticancer activity against the cell lines, particularly human cancer cell lines MCF7...

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Detalles Bibliográficos
Autores principales: Voggu, Ramakrishna, Karmakar, Arundhati, Puli, Venkat Swamy, Damerla, V. Surendra Babu, Mogili, Padma, Amaladass, P., Chidara, Sridhar, Pasunooti, Kalyan Kumar, Gupta, Sarika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343707/
https://www.ncbi.nlm.nih.gov/pubmed/37446626
http://dx.doi.org/10.3390/molecules28134965