Anti-α-Glucosidase, SAR Analysis, and Mechanism Investigation of Indolo[1,2-b]isoquinoline Derivatives

To find potential α-glucosidase inhibitors, indolo[1,2-b]isoquinoline derivatives (1–20) were screened for their α-glucosidase inhibitory effects. All derivatives presented potential α-glucosidase inhibitory effects with IC(50) values of 3.44 ± 0.36~41.24 ± 0.26 μM compared to the positive control a...

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Detalles Bibliográficos
Autores principales: Li, Mengyue, Li, Lin, Lu, Li, Xu, Xuetao, Hu, Jinhui, Peng, Jin-Bao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343752/
https://www.ncbi.nlm.nih.gov/pubmed/37446942
http://dx.doi.org/10.3390/molecules28135282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343752/
https://www.ncbi.nlm.nih.gov/pubmed/37446942
http://dx.doi.org/10.3390/molecules28135282

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