Cargando…

The Finally Rewarding Search for A Cytotoxic Isosteviol Derivative

Acid hydrolysis of stevioside resulted in a 63% yield of isosteviol (1), which served as a starting material for the preparation of numerous amides. These compounds were tested for cytotoxic activity, employing a panel of human tumor cell lines, and almost all amides were found to be non-cytotoxic....

Descripción completa

Detalles Bibliográficos
Autores principales: Heisig, Julia, Heise, Niels V., Hoenke, Sophie, Ströhl, Dieter, Csuk, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343758/
https://www.ncbi.nlm.nih.gov/pubmed/37446613
http://dx.doi.org/10.3390/molecules28134951