Cargando…
The Finally Rewarding Search for A Cytotoxic Isosteviol Derivative
Acid hydrolysis of stevioside resulted in a 63% yield of isosteviol (1), which served as a starting material for the preparation of numerous amides. These compounds were tested for cytotoxic activity, employing a panel of human tumor cell lines, and almost all amides were found to be non-cytotoxic....
Autores principales: | Heisig, Julia, Heise, Niels V., Hoenke, Sophie, Ströhl, Dieter, Csuk, René |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343758/ https://www.ncbi.nlm.nih.gov/pubmed/37446613 http://dx.doi.org/10.3390/molecules28134951 |
Ejemplares similares
-
Rhodamine 101 Conjugates of Triterpenoic Amides Are of Comparable Cytotoxicity as Their Rhodamine B Analogs
por: Heise, Niels V., et al.
Publicado: (2022) -
Developing an Amide-Spacered Triterpenoid Rhodamine Hybrid of Nano-Molar Cytotoxicity Combined with Excellent Tumor Cell/Non-Tumor Cell Selectivity
por: Heise, Niels V., et al.
Publicado: (2023) -
Small Structural Differences Govern the Carbonic Anhydrase II Inhibition Activity of Cytotoxic Triterpene Acetazolamide Conjugates
por: Denner, Toni C., et al.
Publicado: (2023) -
Synthesis and In Silico Docking of New Pyrazolo[4,3-e]pyrido[1,2-a]pyrimidine-based Cytotoxic Agents
por: Horchani, Mabrouk, et al.
Publicado: (2021) -
The Presence of a Cyclohexyldiamine Moiety Confers Cytotoxicity to Pentacyclic Triterpenoids
por: Hoenke, Sophie, et al.
Publicado: (2021)