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Icariin Promotes Osteogenic Differentiation in a Cell Model with NF1 Gene Knockout by Activating the cAMP/PKA/CREB Pathway

Neurofibromatosis type 1 is a rare autosomal dominant genetic disorder, with up to 50% of patients clinically displaying skeletal defects. Currently, the pathogenesis of bone disorders in NF1 patients is unclear, and there are no effective preventive and treatment measures. In this study, we found t...

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Detalles Bibliográficos
Autores principales: Chen, Meng, Lu, Lianhua, Cheng, Dong, Zhang, Jing, Liu, Xinyong, Zhang, Jianli, Zhang, Tianliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343815/
https://www.ncbi.nlm.nih.gov/pubmed/37446790
http://dx.doi.org/10.3390/molecules28135128