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Synthesis and Characterization of Dimeric Artesunate Glycerol Monocaprylate Conjugate and Formulation of Nanoemulsion Preconcentrate

Malaria is one of the major life-threatening health problems worldwide. Artesunate is the most potent antimalarial drug to combat severe malaria. However, development of drug resistance, short plasma half-life, and poor bioavailability limit the efficacy of this drug. Here, we applied the dimerizati...

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Detalles Bibliográficos
Autores principales: Hore, Rana, Hasan, Nazmul, Mäder, Karsten, Kressler, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343907/
https://www.ncbi.nlm.nih.gov/pubmed/37446870
http://dx.doi.org/10.3390/molecules28135208