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Oxoglaucine Suppresses Hepatic Fibrosis by Inhibiting TGFβ-Induced Smad2 Phosphorylation and ROS Generation

Hepatic fibrosis is the first stage of liver disease, and can progress to a chronic status, such as cirrhosis or hepatocellular carcinoma. Excessive production of extracellular matrix (ECM) components plays an important role in the development of fibrosis. Mechanistically, transforming growth factor...

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Detalles Bibliográficos
Autores principales: Azamov, Bakhovuddin, Lee, Kwang-Min, Hur, Jin, Muradillaeva, Shakhnoza, Shim, Wan-Seog, Lee, Chanhee, Song, Parkyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343928/
https://www.ncbi.nlm.nih.gov/pubmed/37446633
http://dx.doi.org/10.3390/molecules28134971