Cargando…
Oxoglaucine Suppresses Hepatic Fibrosis by Inhibiting TGFβ-Induced Smad2 Phosphorylation and ROS Generation
Hepatic fibrosis is the first stage of liver disease, and can progress to a chronic status, such as cirrhosis or hepatocellular carcinoma. Excessive production of extracellular matrix (ECM) components plays an important role in the development of fibrosis. Mechanistically, transforming growth factor...
Autores principales: | Azamov, Bakhovuddin, Lee, Kwang-Min, Hur, Jin, Muradillaeva, Shakhnoza, Shim, Wan-Seog, Lee, Chanhee, Song, Parkyong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343928/ https://www.ncbi.nlm.nih.gov/pubmed/37446633 http://dx.doi.org/10.3390/molecules28134971 |
Ejemplares similares
-
Matrine Suppresses Pancreatic Fibrosis by Regulating TGF-β/Smad Signaling in Rats
por: Liu, Pi, et al.
Publicado: (2019) -
Tranilast Inhibits Pulmonary Fibrosis by Suppressing TGFβ/SMAD2 Pathway
por: Kato, Motoyasu, et al.
Publicado: (2020) -
Aspirin attenuates liver fibrosis by suppressing TGF-β1/Smad signaling
por: Sun, Yimin, et al.
Publicado: (2022) -
Glutathione prevents high glucose-induced pancreatic fibrosis by suppressing pancreatic stellate cell activation via the ROS/TGFβ/SMAD pathway
por: Zhang, Jitai, et al.
Publicado: (2022) -
TGF-β/Smad signaling in renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2015)