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Significant response to margetuximab in Chinese HER2-positive metastatic breast cancer patient who progressed after second-line targeted therapy

Activation of the antibody-dependent cellular cytotoxicity is one of the key mechanisms of anti-human epidermal growth factor receptor 2 (HER2) monoclonal antibody treatment. Margetuximab is a fragment C (Fc)-modified chimeric anti-HER2 immunoglobulin G1 monoclonal antibody that shares epitope speci...

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Detalles Bibliográficos
Autores principales: Li, Jiaping, Lu, Qianyi, Zhou, Hanxing, Xu, Fei, Huang, Jiajia, Hong, Ruoxi, Wang, Shusen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344428/
https://www.ncbi.nlm.nih.gov/pubmed/36729856
http://dx.doi.org/10.1097/CAD.0000000000001471