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Ferrostatin-1 attenuates brain injury in animal model of subarachnoid hemorrhage via phospholipase A2 activity of PRDX6

Subarachnoid hemorrhage (SAH) is an acute catastrophic neurological disorder with high morbidity and mortality. Ferroptosis is one of the pathophysiological processes during secondary brain injury of SAH, which could be inhibited by ferrostatin-1 (Fer-1) effectively. Peroxiredoxin6 (PRDX6) is an ant...

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Detalles Bibliográficos
Autores principales: Wang, Huiqing, Zhou, Yao, Zhao, Mingpei, Yu, Lianghong, Lin, Yuanxiang, Kang, Dezhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344434/
https://www.ncbi.nlm.nih.gov/pubmed/37395228
http://dx.doi.org/10.1097/WNR.0000000000001931