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A novel ribociclib derivative WXJ-103 exerts anti-breast cancer effect through CDK4/6

The triple-negative breast cancer (TNBC) subtype is the most aggressive type of breast cancer with a low survival prognosis and high recurrence rate. There is currently no effective treatment to improve it. In this work, we explored the effect of a synthetic compound named WXJ-103 on several aspects...

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Detalles Bibliográficos
Autores principales: Ji, Jing, Zhang, Zhen, He, Xingbei, Pan, Gang, Li, Guanchu, Lv, Jinyu, Xu, Yuxin, Xie, Mengru, Feng, Jing, Wang, Weiling, Liu, Bin, Ma, Jinming, Wang, Xiujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344442/
https://www.ncbi.nlm.nih.gov/pubmed/36729405
http://dx.doi.org/10.1097/CAD.0000000000001475