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Early stages in Aβ1-42 spontaneous aggregation: An unbiased dataset from coarse-grained molecular dynamics simulations

The small soluble aggregates of Aβ(1-42) are broadly documented as potential targets for the development of new compounds with the capacity to inhibit the early stages of Alzheimer´s disease. Nevertheless, Aβ(1-42) peptides show an intrinsically disordered character with a high propensity for aggreg...

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Detalles Bibliográficos
Autores principales: Barrera, Exequiel E., Pantano, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344647/
https://www.ncbi.nlm.nih.gov/pubmed/37456111
http://dx.doi.org/10.1016/j.dib.2023.109359