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Frequency changes in HLA‐I alleles: A marker to guide immunotherapy in lung adenocarcinoma patients and its relationship with tumor mutational burden and PD‐L1 expression

BACKGROUND: The aim of the study was to investigate differences in HLA‐I alleles between lung adenocarcinoma patients and healthy controls and determine their association with PD‐L1 expression and tumor mutational burden (TMB) to understand the mechanism underlying lung adenocarcinoma susceptibility...

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Detalles Bibliográficos
Autores principales: Wu, Xuanpeng, Wang, Hao, Xue, Fei, Jiang, Tao, Chen, Nanzheng, Wang, Tianju, Zhang, Yong, Zhang, Guangjian, Fu, Junke, Wu, Qifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344735/
https://www.ncbi.nlm.nih.gov/pubmed/37246469
http://dx.doi.org/10.1111/1759-7714.14939