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Dynamic monitoring of circulating tumor DNA to analyze genetic characteristics and resistance profile of lorlatinib in ALK positive previously treated NSCLC

BACKGROUND: To dynamically monitor the changes of genomic characteristics during lorlatinib treatment and analyze the resistance profile of lorlatinib in ALK‐positive advanced Chinese patients with non‐small cell lung cancer (NSCLC) with first‐ and second‐generation ALK inhibitor resistance. METHODS...

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Detalles Bibliográficos
Autores principales: Ma, Xiya, Zhang, Kun, Xu, Jing, Gao, Hongjun, Yang, Shaoxing, Qin, Haifeng, Wang, Hong, Gao, Fang, Liu, Xiaoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344744/
https://www.ncbi.nlm.nih.gov/pubmed/37265111
http://dx.doi.org/10.1111/1759-7714.14980