Accurate isoform discovery with IsoQuant using long reads

Annotating newly sequenced genomes and determining alternative isoforms from long-read RNA data are complex and incompletely solved problems. Here we present IsoQuant—a computational tool using intron graphs that accurately reconstructs transcripts both with and without reference genome annotation....

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Detalles Bibliográficos
Autores principales: Prjibelski, Andrey D., Mikheenko, Alla, Joglekar, Anoushka, Smetanin, Alexander, Jarroux, Julien, Lapidus, Alla L., Tilgner, Hagen U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344776/
https://www.ncbi.nlm.nih.gov/pubmed/36593406
http://dx.doi.org/10.1038/s41587-022-01565-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344776/
https://www.ncbi.nlm.nih.gov/pubmed/36593406
http://dx.doi.org/10.1038/s41587-022-01565-y

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