Dynamic, adaptive sampling during nanopore sequencing using Bayesian experimental design

Nanopore sequencers can select which DNA molecules to sequence, rejecting a molecule after analysis of a small initial part. Currently, selection is based on predetermined regions of interest that remain constant throughout an experiment. Sequencing efforts, thus, cannot be re-focused on molecules l...

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Detalles Bibliográficos
Autores principales: Weilguny, Lukas, De Maio, Nicola, Munro, Rory, Manser, Charlotte, Birney, Ewan, Loose, Matthew, Goldman, Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344778/
https://www.ncbi.nlm.nih.gov/pubmed/36593407
http://dx.doi.org/10.1038/s41587-022-01580-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344778/
https://www.ncbi.nlm.nih.gov/pubmed/36593407
http://dx.doi.org/10.1038/s41587-022-01580-z

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