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mTORC2–NDRG1–CDC42 axis couples fasting to mitochondrial fission

Fasting triggers diverse physiological adaptations including increases in circulating fatty acids and mitochondrial respiration to facilitate organismal survival. The mechanisms driving mitochondrial adaptations and respiratory sufficiency during fasting remain incompletely understood. Here we show...

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Detalles Bibliográficos
Autores principales: Martinez-Lopez, Nuria, Mattar, Pamela, Toledo, Miriam, Bains, Henrietta, Kalyani, Manu, Aoun, Marie Louise, Sharma, Mridul, McIntire, Laura Beth J., Gunther-Cummins, Leslie, Macaluso, Frank P., Aguilan, Jennifer T., Sidoli, Simone, Bourdenx, Mathieu, Singh, Rajat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344787/
https://www.ncbi.nlm.nih.gov/pubmed/37386153
http://dx.doi.org/10.1038/s41556-023-01163-3