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mTORC2–NDRG1–CDC42 axis couples fasting to mitochondrial fission
Fasting triggers diverse physiological adaptations including increases in circulating fatty acids and mitochondrial respiration to facilitate organismal survival. The mechanisms driving mitochondrial adaptations and respiratory sufficiency during fasting remain incompletely understood. Here we show...
Autores principales: | Martinez-Lopez, Nuria, Mattar, Pamela, Toledo, Miriam, Bains, Henrietta, Kalyani, Manu, Aoun, Marie Louise, Sharma, Mridul, McIntire, Laura Beth J., Gunther-Cummins, Leslie, Macaluso, Frank P., Aguilan, Jennifer T., Sidoli, Simone, Bourdenx, Mathieu, Singh, Rajat |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344787/ https://www.ncbi.nlm.nih.gov/pubmed/37386153 http://dx.doi.org/10.1038/s41556-023-01163-3 |
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