Binding domain on CD22 molecules contributing to the biological activity of T cell-engaging bispecific antibodies

CD22, as the B-cell malignancies antigen, has been targeted for immunotherapies through CAR-T cells, antibody-drug conjugates (ADCs) and immunotoxins via interaction of antibodies with binding domains on the receptor. We hypothesized that avidity and binding domain of antibody to target cells may ha...

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Detalles Bibliográficos
Autores principales: Chen, Jie, Pan, Zhidi, Han, Lei, Liu, Junjun, Yue, Yali, Xiao, Xiaodong, Zhang, Baohong, Wu, Mingyuan, Yuan, Yunsheng, Bian, Yanlin, Jiang, Hua, Xie, Yueqing, Zhu, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344817/
https://www.ncbi.nlm.nih.gov/pubmed/37456045
http://dx.doi.org/10.1016/j.heliyon.2023.e17960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344817/
https://www.ncbi.nlm.nih.gov/pubmed/37456045
http://dx.doi.org/10.1016/j.heliyon.2023.e17960

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