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Cancer associated fibroblast derived SLIT2 drives gastric cancer cell metastasis by activating NEK9

The secretory properties of cancer-associated fibroblasts (CAFs) play predominant roles in shaping a pro-metastatic tumor microenvironment. The present study demonstrated that SLIT2, an axon guidance protein, produced by CAFs and promoted gastric cancer (GC) metastasis in two gastric cancer cell lin...

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Detalles Bibliográficos
Autores principales: Lu, Guofang, Du, Rui, Dong, Jiaqiang, Sun, Yi, Zhou, Fenli, Feng, Fan, Feng, Bin, Han, Ying, Shang, Yulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344862/
https://www.ncbi.nlm.nih.gov/pubmed/37443302
http://dx.doi.org/10.1038/s41419-023-05965-z